One force-distance curve, recorded upon touch of two cells, is a real goldmine. Here the gold is hidden in characteristic featurs of the curve, revealing important parameters of the established 'contact'. The most interesting and valuable parameters are the maximal downward deflection of the cantilever, which is represented by the 'Adhesion Force', and the separation energy which is the green area on the diagram below.
 |
| Characteristic features of a force-distance curve |
Both the adhesion force and separation energy are characteristics of the binding strength between the two interacting cells. The 'indentation ~ elasticity' might be important too, but it is hard to distinguish the contribution of the participating cells. However, it can be regarded as characteristic of the total 'two cell system'.
No comments:
Post a Comment